Cytochrome P450 2C8 Chr. Chromosome 10 (human)[1] Available structuresPDBList of PDB id codes Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes2VN0, 1PQ2, 2NNH, 2NNI, 2NNJ Location (UCSC) Chr 10: 95.04 – 95.07 Mb List of PDB id codes List of PDB id codes2VN0, 1PQ2, 2NNH, 2NNI, 2NNJ UniProt P10632 PubMed search [2] RefSeq (protein) NP_000761NP_001185782NP_001185783NP_001185784 Aliases CYP2C8, CPC8, CYPIIC8, MP-12/MP-20, cytochrome P450 family 2 subfamily C member 8, CYP2C8DM RefSeq (mRNA) NM_000770NM_001198853NM_001198854NM_001198855NM_030878 PDB Human UniProt search: PDBe RCSB Gene ontologyMolecular functionCellular componentBiological process Gene ontologyMolecular function• oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen• caffeine oxidase activity• aromatase activity• oxidoreductase activity• heme binding• metal ion binding• iron ion binding• arachidonic acid epoxygenase activity• monooxygenase activity• estrogen 16-alpha-hydroxylase activity• steroid hydroxylase activity• oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygenCellular component• ร่างแหเอนโดพลาซึม• organelle membrane• เยื่อหุ้ม• intracellular membrane-bounded organelle• endoplasmic reticulum membrane• ไซโทพลาซึมBiological process• omega-hydroxylase P450 pathway• organic acid metabolic process• epoxygenase P450 pathway• drug metabolic process• oxidative demethylation• xenobiotic metabolic process• exogenous drug catabolic process• oxidation-reduction process• lipid hydroxylation• steroid metabolic process• long-chain fatty acid biosynthetic process• estrogen metabolic processSources:Amigo / QuickGO Cellular component • ร่างแหเอนโดพลาซึม• organelle membrane• เยื่อหุ้ม• intracellular membrane-bounded organelle• endoplasmic reticulum membrane• ไซโทพลาซึม External IDs OMIM: 601129 HomoloGene: 117948 GeneCards: CYP2C8 End 95,069,497 bp[1] Ensembl ENSG00000138115 Molecular function • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen• caffeine oxidase activity• aromatase activity• oxidoreductase activity• heme binding• metal ion binding• iron ion binding• arachidonic acid epoxygenase activity• monooxygenase activity• estrogen 16-alpha-hydroxylase activity• steroid hydroxylase activity• oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen Biological process • omega-hydroxylase P450 pathway• organic acid metabolic process• epoxygenase P450 pathway• drug metabolic process• oxidative demethylation• xenobiotic metabolic process• exogenous drug catabolic process• oxidation-reduction process• lipid hydroxylation• steroid metabolic process• long-chain fatty acid biosynthetic process• estrogen metabolic process RNA expression pattern RNA expression patternMore reference expression data BandStart 10q23.33 Gene location (Human)Chr.BandStartEnd Gene location (Human)Chr.Chromosome 10 (human)[1]Band10q23.33Start95,036,772 bp[1]End95,069,497 bp[1] Species Human Entrez 1558
ใกล้เคียง Cytochrome P450 3A4 Cytochrome P450 2B6 Cytochrome P450 3A5 Cytochrome P450 2C9 Cytochrome P450 2A6 Cytochrome P450 2C8 Cytochrome P450 2A7 Cytochrome P450 2A13 Cytochrome P450 3A7 Cytochrome P450 3A43
